Vertebral augmentation complicated by perioperative addisonian crisis

Pain Physician. 2006 Jul;9(3):257-60.

Abstract

Background: We describe a case of perioperative Addisonian crisis induced by vertebral augmentation. While several complications of vertebral augmentation have been reported previously, related to the technical procedure, to our knowledge, perioperative Addisonian crisis from vertebral augmentation has not been reported in the literature.

Objective: To report an Addisonian crisis perioperative to vertebral augmentation.

Design: Case report.

Method: Retrospective case review.

Results: The patient had a history of adrenal insufficiency treated previously with steroids. He developed an L3 vertebral compression fracture, failed conservative therapy and was eventually referred for vertebral augmentation. Immediately after starting the procedure, the patient developed profound hypotension unresponsive to intravenous fluids and vasopressors, consistent with Addisonian crisis. After intravenous steroids had resolved the Addisonian crisis, he underwent vertebral augmentation without further complication.

Conclusion: Addisonian crisis may be triggered by vertebral augmentation. Practitioners need to recognize immediately this potentially lethal disorder in patients with known or suspected adrenal insufficiency and treat with intravenous hydrocortisone.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Addison Disease / complications*
  • Addison Disease / drug therapy
  • Aged, 80 and over
  • Fractures, Compression / complications
  • Fractures, Compression / surgery
  • Humans
  • Hypotension / drug therapy
  • Hypotension / etiology*
  • Intraoperative Complications / drug therapy
  • Intraoperative Complications / etiology*
  • Low Back Pain / etiology
  • Low Back Pain / surgery*
  • Lumbar Vertebrae / diagnostic imaging
  • Lumbar Vertebrae / injuries
  • Lumbar Vertebrae / surgery*
  • Male
  • Radiography
  • Steroids / administration & dosage

Substances

  • Steroids