Long-term results of cricopharyngeal myotomy in oculopharyngeal muscular dystrophy

Otolaryngol Head Neck Surg. 2006 Aug;135(2):218-22. doi: 10.1016/j.otohns.2006.03.015.

Abstract

Objective: To analyze long-term results of extramucosal cricopharyngeal myotomy in oculopharyngeal muscular dystrophy.

Study design: The preoperative and postoperative evaluations including symptoms, type of feeding, weight, and functional examinations were retrospectively evaluated in 39 patients. Results were defined postoperatively as successful, partial, or failed.

Setting: University hospital.

Results: In the short term, 25 patients showed a complete remission of symptoms, 10 showed a marked improvement, and 4 exhibited no improvement at all (success rate of 90%). Long-term evaluation during a mean follow-up of 4 years showed that of the 35 improved patients, 12 exhibited a recurrence of dysphagia (mean time of 39 months). In 3 of these 12 patients, a revision transmucosal endoscopic cricopharyngeal myotomy was performed with a successful outcome in 2. Of the 4 patients who initially showed no improvement, 1 was improved by transmucosal myotomy.

Conclusion: Extramucosal cricopharyngeal myotomy improves dysphagia in oculopharyngeal muscular dystrophy patients during the first few years but one third of the patients exhibited a recurrence of symptoms within 3 years. Revision by transmucosal endoscopic myotomy may be performed.

Ebm rating: C-4.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Deglutition Disorders / etiology
  • Deglutition Disorders / surgery*
  • Digestive System Surgical Procedures
  • Esophageal Sphincter, Upper / surgery*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Muscular Dystrophy, Oculopharyngeal / complications*
  • Muscular Dystrophy, Oculopharyngeal / surgery
  • Reoperation
  • Retrospective Studies
  • Treatment Outcome