[Medical prescriptions in haemodialysis patients: critical analysis]

Nephrol Ther. 2005 Oct;1(4):234-40. doi: 10.1016/j.nephro.2005.08.002. Epub 2005 Oct 3.
[Article in French]

Abstract

Aim: The aim of the study is to analyse haemodialysis patients' prescriptions accordance with legal registrations in 64 chronic haemodialysis patients during a one-month follow-up period.

Results: Patients are taking 9.6+/-3 different drugs. A mean of 2.4+/-1.3 prescriptions per patient disagree with the recommended drug use. The directions for use in this specific population are defective in 89%. Moreover, at least one drug-drug interaction is found in 78% of our patients.

Conclusion: Only 8% of the studied hemodialysis patients benefit from prescriptions in agreement with the legal recordings, as a consequence of the lack of drug studies in this particular population. Therefore, clinicians have to rely on their own experience to establish their prescriptions, which can involve their responsibility in case of litigation. Furthermore, the frequency of drug-drug interactions in these polymedicated patients implies that a close pharmaceutical follow-up should be implemented.

Publication types

  • English Abstract
  • Multicenter Study

MeSH terms

  • Aged
  • Cross-Sectional Studies
  • Drug Interactions
  • Drug Prescriptions / statistics & numerical data*
  • Drug Therapy / standards
  • Female
  • France
  • Humans
  • Male
  • Middle Aged
  • Renal Dialysis*