Abstract
In this issue of Cell, Murgia et al. (2006) confirm that the infectious agent of canine transmissible venereal tumor is the cancer cell itself and that the tumor is clonal in origin. Their findings have implications for understanding the relationship between genome instability and transmissible cancer and for conservation biology, canine genomics, and companion animal medicine.
Publication types
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Comment
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Research Support, N.I.H., Intramural
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Review
MeSH terms
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Animals
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Canidae / genetics*
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Cell Lineage / genetics
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Clone Cells / cytology
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Clone Cells / metabolism
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Disease Transmission, Infectious / veterinary*
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Dog Diseases / genetics*
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Dog Diseases / physiopathology
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Dog Diseases / transmission
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Dogs
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Gene Flow / genetics
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Gene Transfer, Horizontal / genetics
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Sarcoma / genetics*
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Sarcoma / metabolism
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Sarcoma / physiopathology
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Sexual Behavior, Animal / physiology
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Venereal Tumors, Veterinary / genetics*
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Venereal Tumors, Veterinary / physiopathology