[Effect of long-term intake of Y3+ in drinking water on learning-memeory functions and growth-development of rats]

Wei Sheng Yan Jiu. 2006 May;35(3):283-5.
[Article in Chinese]

Abstract

Objective: The aim of this paper was to learn the effect of long-term intake of Y3+ in drinking water on learning-memory function and growth-development of rats.

Methods: The rats were fed with water dissolved different level Y3+ (0, 0.534, 53.4, 5340 mg/L) for 6 months, pregnant rate, survive rate, bear rate, variety in weight were calculated, the learning-memory function was observed by step-down test.

Results: The results showed that a significantly decrease in electric shock period and an increase in incubation period were observed for the low dose group, in contrast, a significantly increase in electric shock period and error times, and an decreases in weight and survive rate were observed for the high dose group.

Conclusion: Y3+ in 0.534 mg/L might improve the function of learning and memory in rats, and that Y3+ in 5340mg/L could restrain both the function of learning-memory functions and growth-development in rats.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Animals, Newborn
  • Body Weight / drug effects*
  • Dose-Response Relationship, Drug
  • Female
  • Male
  • Maze Learning / drug effects*
  • Memory / drug effects
  • Paternal Exposure / adverse effects*
  • Pregnancy
  • Prenatal Exposure Delayed Effects*
  • Random Allocation
  • Rats
  • Rats, Wistar
  • Time Factors
  • Yttrium / administration & dosage
  • Yttrium / toxicity*

Substances

  • Yttrium