Abstract
Mycobacterium tuberculosis causes a lymphatic vasculitis in the lungs of guinea pigs infected by a low-dose aerosol. This observation suggests that in addition to being a direct conduit from the lungs to the regional lymph nodes, pulmonary lymphatics are themselves sites of infection and could be the site of latent infection.
Publication types
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Research Support, N.I.H., Extramural
MeSH terms
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Aerosols
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Animals
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Female
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Guinea Pigs
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Lung / immunology
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Lung / microbiology*
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Lung / pathology
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Lymphatic Vessels / microbiology*
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Lymphatic Vessels / pathology*
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Mycobacterium tuberculosis / isolation & purification*
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Tuberculosis, Pulmonary / immunology*
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Tuberculosis, Pulmonary / pathology*