Abstract
TP0658 (FliW) and its orthologs, conserved proteins of unknown function in Treponema pallidum and other species, interact with a C-terminal region of flagellin (FlaB1-3 in T. pallidum; FliC in most other species). Mutants of orthologs in Bacillus subtilis and Campylobacter jejuni (yviF, CJ1075) showed strongly reduced motility. TP0658 stabilizes flagellin in a way similar to FliS, suggesting that TP0658 is a conserved assembly factor for the bacterial flagellum.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Bacillus subtilis / genetics
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Bacillus subtilis / physiology
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Bacterial Proteins / genetics
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Bacterial Proteins / physiology*
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Campylobacter jejuni / genetics
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Campylobacter jejuni / physiology
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Flagella / genetics
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Flagella / physiology*
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Flagellin / metabolism*
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Movement
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Treponema pallidum / genetics
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Treponema pallidum / physiology*
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Treponema pallidum / ultrastructure
Substances
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Bacterial Proteins
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Flagellin