Abstract
Twenty-one intussusception (IS)-associated and 59 temporally linked adenoviral isolates from clinical infections were compared. Species C (15/21 IS- and 32/59 non-IS-associated isolates) dominated. Of these, serotype 2 (AdV-2) (7/15 IS-associated isolates) and serotype 1 (AdV-1) (16/32 non-IS-associated isolates) were the most commonly identified serotypes. DNA restriction analysis of AdV-2 isolates identified six genomic types; of these, type D2 (3/7 IS- and 8/11 non-IS-associated isolates) was the dominant type after BamHI and SmaI digestion. IS-associated isolates are similar to circulating non-IS-associated strains.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adenovirus Infections, Human / diagnosis
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Adenovirus Infections, Human / epidemiology
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Adenovirus Infections, Human / virology*
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Adenoviruses, Human / classification
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Adenoviruses, Human / genetics*
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Australia / epidemiology
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Child, Preschool
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Deoxyribonuclease BamHI / metabolism
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Deoxyribonucleases, Type II Site-Specific / metabolism
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Humans
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Infant
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Intussusception / diagnosis
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Intussusception / epidemiology
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Intussusception / virology*
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Molecular Epidemiology*
Substances
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Deoxyribonuclease BamHI
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CCCGGG-specific type II deoxyribonucleases
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Deoxyribonucleases, Type II Site-Specific