Variant Salmonella genomic island 1-L antibiotic resistance gene cluster in Salmonella enterica serovar Newport

Antimicrob Agents Chemother. 2006 Nov;50(11):3944-6. doi: 10.1128/AAC.00697-06. Epub 2006 Sep 11.

Abstract

We report a new Salmonella genomic island 1 variant antibiotic resistance gene cluster called SGI1-L in a Salmonella enterica serovar Newport isolate containing a dfrA15 gene cassette conferring resistance to trimethoprim. The isolate carried another class 1 integron containing the aacC5 and aadA7 gene cassettes conferring resistance to gentamicin and streptomycin/spectinomycin, respectively.

MeSH terms

  • Anti-Bacterial Agents / pharmacology
  • Blotting, Southern
  • Drug Resistance, Bacterial / genetics*
  • Gastroenteritis / microbiology
  • Genomic Islands / genetics*
  • Gentamicins / pharmacology
  • Humans
  • Male
  • Multigene Family / genetics*
  • Multigene Family / physiology
  • Reverse Transcriptase Polymerase Chain Reaction
  • Salmonella Infections / microbiology
  • Salmonella enterica / drug effects*
  • Salmonella enterica / genetics*
  • Spectinomycin / pharmacology
  • Streptomycin / pharmacology
  • Trimethoprim / pharmacology

Substances

  • Anti-Bacterial Agents
  • Gentamicins
  • Spectinomycin
  • Trimethoprim
  • Streptomycin