Abstract
Teak ( Tectona grandis L.f., Verbenaceae) sawdust extract inhibited the growth of Aspergillus niger. Centrifugal partition chromatography was used to isolate the active compounds. By (1)H-NMR the active compounds were identified as deoxylapachol and tectoquinone. Two A. niger transgenic strains which show induction of 1,3 -alpha-D-glucan synthase were used as a cell wall damage model. The result showed that deoxylapachol from T. grandis extract induced fungal cell wall stress.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Antifungal Agents / chemistry
-
Antifungal Agents / isolation & purification
-
Antifungal Agents / pharmacology*
-
Aspergillus niger / drug effects*
-
Aspergillus niger / genetics
-
Aspergillus niger / growth & development
-
Cell Wall / drug effects*
-
Chromatography
-
Lamiaceae / chemistry*
-
Naphthoquinones / isolation & purification
-
Naphthoquinones / pharmacology
-
Organisms, Genetically Modified / growth & development
-
Plant Extracts / chemistry
-
Plant Extracts / isolation & purification
-
Plant Extracts / pharmacology*
-
Quinones / isolation & purification
-
Quinones / pharmacology*
Substances
-
Antifungal Agents
-
Naphthoquinones
-
Plant Extracts
-
Quinones
-
deoxylapachol