Abstract
Cytokeratin expression in subungual squamous cell carcinoma was investigated in order to evaluate the origin and state of differentiation of the tumour. The tumour nests contained cytokeratin 14, 16 and 17, which were also expressed in the nail bed. Therefore, cytokeratin expression in subungual squamous cell carcinoma may reflect its indolent clinical prognosis.
MeSH terms
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Aged, 80 and over
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Biomarkers, Tumor / metabolism
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Carcinoma, Squamous Cell / metabolism*
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Carcinoma, Squamous Cell / pathology
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Carcinoma, Squamous Cell / surgery
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Humans
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Keratins / metabolism*
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Male
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Nail Diseases / metabolism*
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Nail Diseases / pathology
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Skin Neoplasms / metabolism*
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Skin Neoplasms / pathology
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Skin Neoplasms / surgery
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Thumb
Substances
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Biomarkers, Tumor
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Keratins