An efficient one-pot, three-component synthesis of indeno[1,2-b]quinoline-9,11(6H,10H)-dione, acridine-1,8(2H,5H)-dione and quinoline-3-carbonitrile derivatives from enaminones

Shu-Jiang Tu; Bo Jiang; Run-Hong Jia; Jun-Yong Zhang; Yan Zhang; Chang-Sheng Yao; Feng Shi

doi:10.1039/b607575d

An efficient one-pot, three-component synthesis of indeno[1,2-b]quinoline-9,11(6H,10H)-dione, acridine-1,8(2H,5H)-dione and quinoline-3-carbonitrile derivatives from enaminones

Org Biomol Chem. 2006 Oct 7;4(19):3664-8. doi: 10.1039/b607575d. Epub 2006 Aug 17.

Authors

Shu-Jiang Tu¹, Bo Jiang, Run-Hong Jia, Jun-Yong Zhang, Yan Zhang, Chang-Sheng Yao, Feng Shi

Affiliation

¹ Department of Chemistry, Xuzhou Normal University, Key Laboratory of Biotechnology for Medicinal Plant Xuzhou, Jiangsu, 211116, PR China. [email protected]

PMID: 16990942
DOI: 10.1039/b607575d

Abstract

An efficient one-pot, three-component method for the preparation of indeno[1,2-b]quinoline-9,11(6H,10H)-dione, acridine-1,8(2H,5H)-dione and various multi-substituted quinoline-3-carbonitrile derivatives has been developed through the Michael addition to enaminones, which was achieved by both microwave irradiation and conventional heating.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Acridines / chemical synthesis*
Acridines / chemistry
Crystallography, X-Ray
Heterocyclic Compounds, 4 or More Rings / chemistry*
Nitriles / chemical synthesis*
Nitriles / chemistry
Quinolines / chemical synthesis*
Quinolines / chemistry
Temperature

Substances

Acridines
Heterocyclic Compounds, 4 or More Rings
Nitriles
Quinolines
quinoline