Conservation and divergence in cellulosome architecture between two strains of Ruminococcus flavefaciens

J Bacteriol. 2006 Nov;188(22):7971-6. doi: 10.1128/JB.00973-06. Epub 2006 Sep 22.

Abstract

A 17-kb scaffoldin gene cluster in Ruminococcus flavefaciens strain FD-1 was compared with the homologous segment published for strain 17. Although the general design of the cluster is identical in the two strains, significant differences in the modular architecture of the scaffoldin proteins were discovered, implying strain-specific divergence in cellulosome organization.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Bacterial Proteins / chemistry*
  • Bacterial Proteins / genetics*
  • Cellulose / metabolism
  • Cellulosomes / chemistry*
  • Cellulosomes / genetics*
  • Cellulosomes / metabolism
  • Genes, Bacterial
  • Multigene Family
  • Phylogeny
  • Ruminococcus / cytology*
  • Ruminococcus / metabolism
  • Sequence Homology

Substances

  • Bacterial Proteins
  • ScaA protein, Ruminococcus
  • ScaB protein, Ruminococcus
  • Cellulose