Cerebral malaria in spite of peripheral parasite clearance in a patient treated with atovaquone/proguanil

Parasitol Res. 2007 Mar;100(4):747-8. doi: 10.1007/s00436-006-0317-6. Epub 2006 Sep 27.

Abstract

Cerebral malaria, the most frequent complication of falciparum malaria, is usually predicted by an increased count of asexual parasites in peripheral blood. We report a case of a female returnee from Ghana who developed cerebral malaria in spite of parasite clearance in peripheral blood after therapy with atovaquone/proguanil.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Animals
  • Antimalarials / therapeutic use*
  • Artemisinins / therapeutic use
  • Artesunate
  • Atovaquone / therapeutic use*
  • Female
  • Humans
  • Malaria, Cerebral / drug therapy*
  • Malaria, Cerebral / parasitology*
  • Plasmodium falciparum / drug effects*
  • Plasmodium falciparum / isolation & purification
  • Proguanil / therapeutic use*
  • Quinine / therapeutic use
  • Sesquiterpenes / therapeutic use

Substances

  • Antimalarials
  • Artemisinins
  • Sesquiterpenes
  • Artesunate
  • Quinine
  • Proguanil
  • Atovaquone