Evidence for independent segregation of the VP6- and NSP4- encoding genes in porcine group A rotavirus G6P[13] strains

Arch Virol. 2007 Feb;152(2):423-9. doi: 10.1007/s00705-006-0848-2. Epub 2006 Sep 28.

Abstract

Molecular characterization of two porcine group A rotavirus strains (HP113 and HP140), detected from eastern India, revealed a VP7 closely related to those of human G6P[14] strains, VP4 with a borderline P[13] genotype, and VP6 related to bovine and human SGI strains rather than porcine SGI and/or SGII group A rotaviruses. Both strains had NSP4 and NSP5 of porcine origin. Therefore, to our knowledge, the present study is the first report of detection of group A rotavirus strains with G6P[13] genotype specificities and provides evidence for independent segregation of the VP6- and NSP4-encoding genes in porcine group A rotaviruses.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Antigens, Viral / genetics*
  • Capsid Proteins / genetics*
  • Genes, Viral*
  • Glycoproteins / genetics*
  • Molecular Sequence Data
  • Phylogeny
  • RNA, Viral / genetics
  • Rotavirus / classification
  • Rotavirus / genetics*
  • Rotavirus / isolation & purification
  • Sequence Homology, Amino Acid
  • Swine
  • Toxins, Biological / genetics*
  • Viral Nonstructural Proteins / genetics*

Substances

  • Antigens, Viral
  • Capsid Proteins
  • Glycoproteins
  • NS28 protein, rotavirus
  • RNA, Viral
  • Toxins, Biological
  • VP6 protein, Rotavirus
  • Viral Nonstructural Proteins