Abstract
The synthesis of virulence factors in the plant pathogen Xanthomonas campestris pathovar campestris is regulated by cell-cell signaling mediated by a diffusible signal factor (DSF), and by the RpfC/RpfG two-component regulatory system. Recent findings have indicated that the perception of the DSF signal requires the RpfC sensor and is linked to the degradation of the intracellular second messenger cyclic di-GMP by the HD-GYP domain regulator RpfG.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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3',5'-Cyclic-GMP Phosphodiesterases / metabolism
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Bacterial Proteins / metabolism
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Cyclic GMP / analogs & derivatives*
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Cyclic GMP / metabolism
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Plants / microbiology
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Protein Structure, Tertiary
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Quorum Sensing
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Second Messenger Systems
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Signal Transduction
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Virulence Factors / metabolism*
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Xanthomonas campestris / metabolism*
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Xanthomonas campestris / pathogenicity*
Substances
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Bacterial Proteins
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RpfG protein, Xanthomonas campestris
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Virulence Factors
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rpfC protein, Xanthomonas
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bis(3',5')-cyclic diguanylic acid
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3',5'-Cyclic-GMP Phosphodiesterases
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Cyclic GMP