[Caenorhabditis elegans: in vivo study model of bacterial virulence]

Pathol Biol (Paris). 2006 Oct-Nov;54(8-9):439-46. doi: 10.1016/j.patbio.2006.07.011. Epub 2006 Oct 5.
[Article in French]

Abstract

The nematode Caenorhabditis elegans presents many advantages as a model system. The worm has recently emerged as a potentially useful tool for the study of host-pathogen interactions. This paper presents advantages and inconveniences of this model, the variety of bacterial pathogens studied, and its use to monitor virulence of Extraintestinal Escherichia coli strains.

MeSH terms

  • Animals
  • Bacterial Infections*
  • Caenorhabditis elegans / microbiology*
  • Disease Models, Animal
  • Escherichia coli / pathogenicity
  • Escherichia coli Infections*
  • Humans
  • Reproducibility of Results
  • Virulence