Sigmoid orthotopic neobladder after radical cystectomy for bladder tumour: an Indian experience

BJU Int. 2007 Feb;99(2):403-6. doi: 10.1111/j.1464-410X.2006.06541.x. Epub 2006 Oct 11.

Abstract

Objective: To determine the long-term results of constructing a sigmoid neobladder after radical cystectomy for transitional cell carcinoma (TCC) of the urinary bladder.

Patients and methods: The study included 170 patients with TCC of the bladder and a normal sigmoid colon. After radical cystectomy the neobladder was formed by completely detubularizing an isolated sigmoid colon segment. Subsequently patients were followed by clinical, biochemical, radiological and urodynamic assessments.

Results: Four patients died soon after surgery; the neobladder-related delayed complications were death in three patients, loss of five renal units, and electrolyte imbalance in five patients. Uretero-intestinal anastomotic narrowing was another frequent delayed complication. Most (97%) patients had nocturnal incontinence, and most voided with a good stream with a minimal postvoid residual urine volume.

Conclusion: The sigmoid neobladder, despite some limitations, is the best option for diverting urine after radical cystectomy.

MeSH terms

  • Adult
  • Aged
  • Carcinoma, Transitional Cell / mortality
  • Carcinoma, Transitional Cell / physiopathology
  • Carcinoma, Transitional Cell / surgery*
  • Colon, Sigmoid / surgery*
  • Cystectomy / methods
  • Follow-Up Studies
  • Humans
  • India
  • Male
  • Middle Aged
  • Nocturnal Enuresis / etiology
  • Postoperative Complications / etiology
  • Postoperative Complications / mortality
  • Treatment Outcome
  • Urinary Bladder Neoplasms / mortality
  • Urinary Bladder Neoplasms / physiopathology
  • Urinary Bladder Neoplasms / surgery*
  • Urinary Diversion / methods*
  • Urinary Reservoirs, Continent*
  • Urodynamics