Evaluation of Entamoeba histolytica antigen and antibody point-of-care tests for the rapid diagnosis of amebiasis

J Clin Microbiol. 2006 Dec;44(12):4569-71. doi: 10.1128/JCM.01979-06. Epub 2006 Oct 11.

Abstract

The bedside diagnosis of amebiasis could improve patient care. In Bangladesh and Vietnam, a novel and simple-to-use Entamoeba histolytica rapid antigen test had 97% sensitivity and 100% specificity compared to the results of a standard enzyme-linked immunosorbent assay antigen detection method, and a rapid antibody test had 89 to 100% sensitivity and 89 to 95% specificity.

Publication types

  • Comparative Study
  • Evaluation Study
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antibodies, Protozoan / blood*
  • Antigens, Protozoan / analysis*
  • Entamoeba histolytica / immunology*
  • Entamoeba histolytica / isolation & purification*
  • Entamoebiasis / diagnosis*
  • Enzyme-Linked Immunosorbent Assay
  • Feces / chemistry
  • Humans
  • Point-of-Care Systems*
  • Reagent Kits, Diagnostic
  • Sensitivity and Specificity
  • Serologic Tests

Substances

  • Antibodies, Protozoan
  • Antigens, Protozoan
  • Reagent Kits, Diagnostic