Correlates of suicide attempt history in bipolar disorder: a stress-diathesis perspective

Bipolar Disord. 2006 Oct;8(5 Pt 2):551-7. doi: 10.1111/j.1399-5618.2006.00304.x.

Abstract

Objectives: Distinguishing clinical characteristics of bipolar patients who have made a suicide attempt may help to identify at-risk individuals. We sought to identify such factors and to consider them within a stress-diathesis model of suicidal behavior.

Methods: Patients with bipolar disorder (N = 96) were compared with respect to the presence or absence at baseline evaluation of a history of suicide attempt. We used multiple logistic regression analysis to assess the unique associations of independent variables to history of a past suicide attempt.

Results: The regression analysis showed that a history of suicide attempt in bipolar disorder was associated with greater recent suicidal ideation, more psychiatric hospitalizations, lifetime aggressive traits and an earlier age at onset of a first mood episode.

Conclusions: Aggressive traits and early treatment of mood disorders, especially major depressive episodes, are potential targets for suicide prevention in bipolar disorder.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aggression / psychology
  • Bipolar Disorder / drug therapy
  • Bipolar Disorder / epidemiology*
  • Bipolar Disorder / psychology
  • Demography
  • Depressive Disorder, Major / drug therapy
  • Depressive Disorder, Major / epidemiology
  • Depressive Disorder, Major / psychology
  • Disease Susceptibility
  • Female
  • Hostility
  • Humans
  • Life Change Events
  • Male
  • Middle Aged
  • Risk Factors
  • Severity of Illness Index
  • Stress, Psychological / epidemiology*
  • Stress, Psychological / psychology
  • Suicide / psychology
  • Suicide / statistics & numerical data
  • Suicide, Attempted / psychology
  • Suicide, Attempted / statistics & numerical data*
  • Surveys and Questionnaires