Clinical challenges presented by three simultaneous solid tumors

Gynecol Oncol. 2006 Dec;103(3):1159-63. doi: 10.1016/j.ygyno.2006.08.050. Epub 2006 Oct 20.

Abstract

Background: Simultaneous tumors are rare, and their management can be challenging. The simultaneous presentation of cervical carcinoma, renal cell carcinoma, and appendiceal carcinoma has not been previously described.

Case: A 57-year-old woman presented with cervical cancer. During her workup, she was diagnosed with mucinous appendiceal carcinoma and clear cell carcinoma of the kidney. One year following surgery, she remains without evidence of disease and with continually improving nutritional status.

Conclusion: When simultaneous tumors are diagnosed, optimal care requires the creative expertise of a multidisciplinary team. Standard sequential therapies may be problematic in patients undergoing major surgery to treat another primary tumor, and sequential treatment delays rather than combining therapies can jeopardize cure. Treatment planning should utilize a coordinated multidisciplinary approach.

Publication types

  • Case Reports
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adenocarcinoma, Clear Cell / diagnosis
  • Adenocarcinoma, Clear Cell / pathology
  • Adenocarcinoma, Clear Cell / therapy
  • Adenocarcinoma, Mucinous / diagnosis
  • Adenocarcinoma, Mucinous / pathology
  • Adenocarcinoma, Mucinous / therapy
  • Appendiceal Neoplasms / diagnosis
  • Appendiceal Neoplasms / pathology
  • Appendiceal Neoplasms / therapy
  • Carcinoma, Squamous Cell / diagnosis
  • Carcinoma, Squamous Cell / pathology
  • Carcinoma, Squamous Cell / therapy
  • Combined Modality Therapy
  • Diagnosis, Differential
  • Female
  • Humans
  • Kidney Neoplasms / diagnosis
  • Kidney Neoplasms / pathology
  • Kidney Neoplasms / therapy
  • Middle Aged
  • Neoplasm Staging
  • Neoplasms, Multiple Primary / diagnosis*
  • Neoplasms, Multiple Primary / diagnostic imaging
  • Neoplasms, Multiple Primary / pathology
  • Neoplasms, Multiple Primary / therapy
  • Radiography
  • Uterine Cervical Neoplasms / diagnosis
  • Uterine Cervical Neoplasms / pathology
  • Uterine Cervical Neoplasms / therapy