Treatment disparities in Hispanic rectal cancer patients: a SEER database study

Am Surg. 2006 Oct;72(10):906-8.

Abstract

Although Hispanics demonstrate a low overall incidence of rectal cancer, mortality rates have not decreased relative to non-Hispanic whites. To determine if this was in part due to racial disparities in care, we compared rates of neoadjuvant therapy and sphincter-preserving surgery between Hispanics and non-Hispanic whites diagnosed with rectal cancer using the Surveillance, Epidemiology, and End Results (SEER) database. The study population was comprised of 2,573 Hispanics (55.4% male) and 28,395 non-Hispanic whites (56.6% male). Rates of neoadjuvant radiation were 13.5 per cent for Hispanics compared with 10.4 per cent for non-Hispanic whites (P < 0.001). In a Cox proportional hazards model adjusting for nodal status, tumor size, and T stage, non-Hispanic whites were significantly less likely to have received neoadjuvant therapy (hazard ratio, 0.72; P < 0.001; 95% confidence interval 0.63-0.83). Rates of sphincter preservation were 67 per cent for Hispanics and 70 per cent for non-Hispanic whites (P = 0.003). Non-Hispanic whites were significantly more likely to have received a sphincter-preserving operation than Hispanics (hazard ratio, 1.076; P = 0.019; 95% confidence interval 1.02-1.27). We conclude that Hispanics are significantly more likely to receive neoadjuvant therapy but are less likely to receive sphincter-sparing operations for rectal cancer compared with non-Hispanic whites. Further studies are required to assess the impact of these treatment disparities on patient outcome.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Anal Canal / surgery
  • Female
  • Hispanic or Latino* / statistics & numerical data
  • Humans
  • Lymphatic Metastasis / pathology
  • Male
  • Middle Aged
  • Neoadjuvant Therapy / statistics & numerical data
  • Neoplasm Staging
  • Proportional Hazards Models
  • Radiotherapy, Adjuvant / statistics & numerical data
  • Rectal Neoplasms / ethnology*
  • Rectal Neoplasms / mortality
  • SEER Program* / statistics & numerical data
  • Treatment Outcome
  • United States / epidemiology
  • White People / statistics & numerical data