Early detection of viral excretion from experimentally infected goats with peste-des-petits ruminants virus

Prev Vet Med. 2007 Jan 16;78(1):85-8. doi: 10.1016/j.prevetmed.2006.09.003. Epub 2006 Oct 24.

Abstract

We observed 15 goats for 9 days after subcutaneous infection with 10(3) TCID(50) with isolates of peste-des-petits ruminants virus from Africa and India and five concurrent, uninfected control goats. Typical clinical signs of the infection were present in all 15 infected goats by day 8 and in most by day 6 and some signs were present by day 4. However, 6 out of 15 goats already have detectable virus shedding by day 3 and four more were shedding by day 4 and every goat had virus shedding for at least 1 day before the recognition of clinical signs. This experiment indicates that incubatory carriers therefore might play a role in the transmission of PPRV among small ruminants.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Africa South of the Sahara
  • Animals
  • Body Temperature
  • Carrier State / veterinary*
  • Carrier State / virology
  • Goat Diseases / transmission
  • Goat Diseases / virology*
  • Goats
  • Peste-des-Petits-Ruminants / transmission
  • Peste-des-Petits-Ruminants / veterinary*
  • Peste-des-Petits-Ruminants / virology
  • Peste-des-petits-ruminants virus / genetics
  • Peste-des-petits-ruminants virus / growth & development*
  • RNA, Viral / chemistry
  • RNA, Viral / genetics
  • Random Allocation
  • Reverse Transcriptase Polymerase Chain Reaction / veterinary
  • Virus Shedding

Substances

  • RNA, Viral