Criteria for drugs used in pre-exposure prophylaxis trials against HIV infection

PLoS Med. 2006 Nov;3(11):e454. doi: 10.1371/journal.pmed.0030454.

Abstract

The authors formulate criteria for an optimal pre-exposure prophylaxis drug candidate, and evaluate existing antiviral drug classes for their suitability.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Anti-HIV Agents / therapeutic use
  • Anti-Retroviral Agents / economics
  • Anti-Retroviral Agents / standards*
  • Anti-Retroviral Agents / therapeutic use*
  • Clinical Trials as Topic*
  • Cost-Benefit Analysis
  • Drug Combinations
  • HIV Infections / prevention & control*
  • Humans
  • Lamivudine / therapeutic use
  • Research Design

Substances

  • Anti-HIV Agents
  • Anti-Retroviral Agents
  • Drug Combinations
  • Lamivudine