Heterogeneous epileptogenicity and cortical function within malformations of cortical development: a case report

J Neurol Sci. 2006 Dec 21;251(1-2):129-33. doi: 10.1016/j.jns.2006.09.016. Epub 2006 Nov 13.

Abstract

The authors report a 24-year-old patient with intractable partial epilepsy and massive malformations of cortical development (MCD). Subdural EEG recordings of habitual seizures showed heterogeneous epileptogenicity, and visual evoked potential was recorded within the MCD just adjacent to the most active epileptogenic focus. Resection of the small cortical area presumably with core epileptogenicity, while sparing the cortical functional area, improved seizure outcome without any postoperative functional deficits.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Brain Mapping*
  • Electrodes
  • Electroencephalography / methods
  • Epilepsies, Partial / pathology
  • Epilepsies, Partial / physiopathology*
  • Evoked Potentials, Visual / physiology
  • Female
  • Humans
  • Magnetic Resonance Imaging / methods
  • Visual Cortex / physiopathology*