Complications involving the enteric anastomosis site, including intra-abdominal abscess and enterocutaneous fistula formation, have been well documented following pancreas transplantation. Although uncommon, these complications remain particularly difficult to manage and frequently mandate surgical re-exploration. In this manuscript, we will review three cases of enterocutaneous fistula in pancreas transplant recipients managed nonoperatively with percutaneous drainage and subsequent occlusion of the tract with fibrin sealant.