Suzuki-Miyaura cross-coupling reactions of benzyl halides with potassium aryltrifluoroborates

J Org Chem. 2006 Nov 24;71(24):9198-202. doi: 10.1021/jo061699f.

Abstract

[reaction: see text] The palladium-catalyzed cross-coupling of potassium aryltrifluoroborates with benzylic halides occurs in good yield with high functional group tolerance. The increased stability of potassium aryltrifluoroborates compared to other boron coupling partners makes this an effective route to functionalized methylene-linked biaryl systems.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Borates / chemistry*
  • Halogens / chemistry*

Substances

  • Borates
  • Halogens