Unusual clinical presentation of primary hypothyroidism in a very young infant caused by autoimmune thyroiditis: case report and update of the literature

Janna Mittnacht; Fabian Schmidt; Friedrich Ebinger; Markus Bettendorf

doi:10.1007/s00431-006-0323-9

Unusual clinical presentation of primary hypothyroidism in a very young infant caused by autoimmune thyroiditis: case report and update of the literature

Eur J Pediatr. 2007 Aug;166(8):881-3. doi: 10.1007/s00431-006-0323-9. Epub 2006 Nov 21.

Authors

Janna Mittnacht¹, Fabian Schmidt, Friedrich Ebinger, Markus Bettendorf

Affiliation

¹ Division of Paediatric Endocrinology and Diabetes, Children's Hospital, University of Heidelberg, Im Neuenheimer Feld 153, 69120 Heidelberg, Germany. [email protected]

PMID: 17120037
DOI: 10.1007/s00431-006-0323-9

Abstract

Acquired primary hypothyroidism in infancy can be related to autoimmune thyroiditis and can present with unusual symptoms, such as muscle pseudohypertrophy and pituitary tumor. This condition can cause permanent deficits in psychomotor development and growth despite adequate replacement with L: -thyroxine.

Publication types

Case Reports

MeSH terms

Autoantibodies / blood
Developmental Disabilities / etiology
Hormone Replacement Therapy
Humans
Hypothyroidism / diagnosis
Hypothyroidism / drug therapy
Hypothyroidism / etiology*
Infant
Male
Thyroid Function Tests
Thyroiditis, Autoimmune / complications*
Thyroiditis, Autoimmune / diagnosis
Thyroxine / therapeutic use

Substances

Autoantibodies
Thyroxine