Changes within the thyroid axis during the course of critical illness

Liese Mebis; Yves Debaveye; Theo J Visser; Greet Van den Berghe

doi:10.1016/j.ecl.2006.09.009

Changes within the thyroid axis during the course of critical illness

Endocrinol Metab Clin North Am. 2006 Dec;35(4):807-21, x. doi: 10.1016/j.ecl.2006.09.009.

Authors

Liese Mebis¹, Yves Debaveye, Theo J Visser, Greet Van den Berghe

Affiliation

¹ Department of Intensive Care, Catholic University of Leuven, Leuven, Belgium.

PMID: 17127148
DOI: 10.1016/j.ecl.2006.09.009

Abstract

This article reviews the mechanisms behind the observed changes in plasma thyroid hormone levels in the acute phase and the prolonged phase of critical illness. It focuses on the neuroendocrinology of the low triiodothyronine syndrome and on thyroid hormone metabolism by deiodination and transport.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Critical Care / methods
Critical Illness* / therapy
Humans
Hypothalamo-Hypophyseal System / physiopathology*
Pituitary-Adrenal System / physiopathology*
Thyroid Gland / physiopathology*
Thyroid Hormones / physiology

Substances

Thyroid Hormones