A satellite RNA of barley yellow dwarf virus contains a novel hammerhead structure in the self-cleavage domain

Virology. 1991 Aug;183(2):711-20. doi: 10.1016/0042-6822(91)91000-7.

Abstract

An RNA molecule with properties of a satellite RNA was found in an isolate of barley yellow dwarf virus (BYDV), RPV serotype. It is 322 nucleotide long, single-stranded, and does not hybridize to the viral genome. Dimers of the RNA, which presumably represent replicative intermediates, were able to self-cleave into monomers. In vitro transcripts from cDNA clones were capable of self-cleavage in both the plus (encapsidated) and minus orientations. The sequence flanking the minus strand cleavage site contained a consensus "hammerhead" structure, similar to those found in other self-cleaving satellite RNAs. Although related to the hammerhead structure, sequences flanking the plus strand termini showed differences from the consensus and may be folded into a different structure containing a pseudo-knot.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Base Sequence
  • Cloning, Molecular
  • Hordeum
  • Molecular Sequence Data
  • Molecular Weight
  • Nucleic Acid Conformation
  • Plant Viruses / genetics*
  • RNA / chemistry*
  • RNA / metabolism
  • RNA, Satellite
  • RNA, Viral / chemistry*
  • RNA, Viral / metabolism

Substances

  • RNA, Satellite
  • RNA, Viral
  • RNA

Associated data

  • GENBANK/M55473
  • GENBANK/M55474
  • GENBANK/M55475
  • GENBANK/M55476
  • GENBANK/M55477
  • GENBANK/M55478
  • GENBANK/M63666
  • GENBANK/M64315
  • GENBANK/M64316
  • GENBANK/S42528