Plasmid-mediated KPC-2 in a Klebsiella pneumoniae isolate from China

Antimicrob Agents Chemother. 2007 Feb;51(2):763-5. doi: 10.1128/AAC.01053-06. Epub 2006 Dec 4.

Abstract

A carbapenem-resistant isolate of Klebsiella pneumoniae producing class A carbapenemase KPC-2 was identified in Zhejiang, China. The KPC-2 gene was located on an approximately 60-kb plasmid in a genetic environment partially different from that of blaKPC-2 in the isolates from the United States and Colombia.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Carbapenems / pharmacology
  • China
  • Hospitals, University
  • Humans
  • Klebsiella pneumoniae* / drug effects
  • Klebsiella pneumoniae* / enzymology
  • Klebsiella pneumoniae* / genetics
  • Molecular Sequence Data
  • Plasmids
  • beta-Lactam Resistance
  • beta-Lactamases / genetics*

Substances

  • Carbapenems
  • beta-lactamase KPC-2
  • beta-Lactamases

Associated data

  • GENBANK/DQ897687