New approximations to the Malthusian parameter

Biometrics. 2006 Dec;62(4):1216-23. doi: 10.1111/j.1541-0420.2006.00564.x.

Abstract

Approximations to the Malthusian parameter of an age-dependent branching process are obtained in terms of the moments of the lifetime distribution, by exploiting a link with renewal theory. In several examples, the new approximations are more accurate than those currently in use, even when based on only the first two moments. The new approximations are extended to include a form of asymmetric cell division that occurs in some species of yeast. When used for inference, the new approximations are shown to have high efficiency.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biometry / methods*
  • Cell Cycle
  • Cell Division
  • Models, Biological*
  • Models, Statistical*
  • Population Dynamics*
  • Yeasts / cytology