Abstract
The first enantioselective synthesis of C(3) fluoro-MEP is herein reported. The synthetic pathway developed takes advantage of a selective hydrofluorination of a 2,3-epoxy-1-alcohol to introduce the required tertiary fluoride unit.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alcohols / chemistry
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Erythritol / analogs & derivatives*
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Erythritol / chemical synthesis*
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Erythritol / chemistry
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Fluorine / chemistry
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Molecular Structure
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Stereoisomerism
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Sugar Phosphates / chemical synthesis*
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Sugar Phosphates / chemistry*
Substances
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Alcohols
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Sugar Phosphates
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phosphoric acid 3-fluoro-2,4-dihdyroxy-3-methylbutyl ester
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Fluorine
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erythritol 4-phosphate
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Erythritol