Carbohydrate antigens: synthesis aspects and immunological applications in cancer

Mini Rev Med Chem. 2006 Dec;6(12):1357-73. doi: 10.2174/138955706778992996.

Abstract

Tumor Associated Carbohydrate Antigens (TACAs) constitute powerful tools as tumor markers and as targets for anticancer immunotherapy. In this review, methods of production of glycopeptide-based vaccines, as well as results of preclinical and clinical studies in cancer patients are discussed.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Antigens, Neoplasm / biosynthesis*
  • Antigens, Neoplasm / immunology
  • Biomarkers, Tumor / biosynthesis*
  • Biomarkers, Tumor / immunology
  • Glycosylation
  • Humans
  • Neoplasms / diagnosis
  • Neoplasms / immunology*

Substances

  • Antigens, Neoplasm
  • Biomarkers, Tumor