Local thrombolytic treatment of cerebral venous thrombosis in three paediatric patients

Mohammad Wasay; Rohit Bakshi; Alper Dai; Steve Roach

Local thrombolytic treatment of cerebral venous thrombosis in three paediatric patients

J Pak Med Assoc. 2006 Nov;56(11):555-6.

Authors

Mohammad Wasay¹, Rohit Bakshi, Alper Dai, Steve Roach

Affiliation

¹ Department of Neurology, The Aga Khan University, Karachi, Turkey.

PMID: 17183991

Abstract

There is increasing evidence that local thrombolysis can be used with relative safety and efficacy in adults with superior sagittal sinus thrombosis (SSST). However, little data is available on the use of local thrombolysis in children with SSST. We report three patients who received local thrombolysis for dural sinus thrombosis. Two patients received urokinase and one patient received urokinase followed by local TPA infusion. Recanalization was achieved in two patients.

Publication types

Case Reports

MeSH terms

Cerebral Veins / pathology*
Child
Child, Preschool
Cranial Sinuses / pathology*
Fatal Outcome
Female
Humans
Infant, Newborn
Male
Sinus Thrombosis, Intracranial / drug therapy*
Sinus Thrombosis, Intracranial / pathology
Thrombolytic Therapy*
Urokinase-Type Plasminogen Activator / administration & dosage
Urokinase-Type Plasminogen Activator / therapeutic use*
Venous Thrombosis / drug therapy*
Venous Thrombosis / pathology

Substances

Urokinase-Type Plasminogen Activator