[Improved method of acute myocardial ischemic rat model]

Fa Yi Xue Za Zhi. 2006 Oct 15;22(5):321-3.
[Article in Chinese]

Abstract

Objective: To improve the successful rate of operation and the livability in establishing acute myocardial ischemic rat model.

Methods: The successful rate of animal experiment is compared between traditional method and improved method.

Results: The successful rate of improved method was 90%, which was much higher than 30% in successful rate of traditional method.

Conclusion: The improved method may reduce the difficulty of operation remarkably and cut down the experiment expenditure, which is superior to traditional method.

Publication types

  • Comparative Study
  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Disease
  • Anesthesia, General / methods*
  • Animals
  • Coronary Vessels / surgery*
  • Disease Models, Animal*
  • Intubation, Intratracheal / methods*
  • Ketamine / administration & dosage
  • Ketamine / chemistry
  • Male
  • Myocardial Ischemia / pathology*
  • Rats
  • Rats, Sprague-Dawley

Substances

  • Ketamine