Abstract
Xenofuranones A (1) and B (2) have been isolated from cultures of the insect-pathogenic bacterium Xenorhabdus szentirmaii, and their structures were elucidated by NMR and mass spectroscopy. Both compounds show similarities to fungal furanones, and their biosynthesis was studied using a reversed approach by feeding putative 12C precursors to an overall 13C background in small-scale experiments followed by gas chromatographic analysis coupled to mass spectrometry.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Feeding Behavior / drug effects
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Furans / chemistry
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Furans / isolation & purification*
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Furans / pharmacology
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Insecta / drug effects
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Mice
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Molecular Structure
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Nuclear Magnetic Resonance, Biomolecular
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Phenylpyruvic Acids / chemistry
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Phenylpyruvic Acids / isolation & purification*
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Phenylpyruvic Acids / pharmacology
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Xenorhabdus / chemistry*
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Xenorhabdus / pathogenicity
Substances
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Furans
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Phenylpyruvic Acids
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xenofuranone A
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xenofuranone B