fMRI reveals novel functional neuroanatomy in a child with perinatal stroke

Neurology. 2006 Dec 26;67(12):2246-9. doi: 10.1212/01.wnl.0000249348.84045.0e.

Abstract

Children who have experienced a perinatal stroke often develop normal language function, but the neurobiologic mechanisms underlying this plasticity remain unclear. In this study, we used fMRI to compare, at two ages, the functional neuroanatomy of a child with perinatal stroke with that of age-appropriate cohorts of typically developing children. Although the data for this child are similar to the control group, there are age-dependent differences.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Brain / pathology*
  • Brain / physiopathology*
  • Brain Mapping*
  • Child
  • Evoked Potentials*
  • Female
  • Humans
  • Infant, Newborn
  • Infant, Newborn, Diseases / pathology
  • Infant, Newborn, Diseases / physiopathology
  • Magnetic Resonance Imaging / methods*
  • Male
  • Stroke / pathology*
  • Stroke / physiopathology*