Synthesis of silafluorenes by iridium-catalyzed [2 + 2 + 2] cycloaddition of silicon-bridged diynes with alkynes

Takanori Matsuda; Sho Kadowaki; Tsuyoshi Goya; Masahiro Murakami

doi:10.1021/ol062732n

Synthesis of silafluorenes by iridium-catalyzed [2 + 2 + 2] cycloaddition of silicon-bridged diynes with alkynes

Org Lett. 2007 Jan 4;9(1):133-6. doi: 10.1021/ol062732n.

Authors

Takanori Matsuda¹, Sho Kadowaki, Tsuyoshi Goya, Masahiro Murakami

Affiliation

¹ Department of Synthetic Chemistry and Biological Chemistry, Kyoto University, Katsura, Kyoto 615-8510, Japan.

PMID: 17192103
DOI: 10.1021/ol062732n

Abstract

[reaction: see text] Silicon-bridged 1,6-diynes underwent [2 + 2 + 2] cycloaddition with alkynes in the presence of an iridium(I)-phosphine catalyst to afford densely substituted silafluorene derivatives. Extended silafluorene skeletons were constructed by the [2 + 2 + 2] cycloaddition of tetraynes.