Immune reconstitution inflammatory syndrome presenting as sinusitis with inflammatory pseudotumor in an HIV-infected patient: a case report and review of the literature

AIDS Patient Care STDS. 2006 Dec;20(12):823-8. doi: 10.1089/apc.2006.20.823.

Abstract

Immune reconstitution inflammatory syndrome (IRIS) encompasses a variety of conditions that occur among HIV-infected patients in a temporal relationship with increases in CD4 cell count as a result of highly active antiretroviral therapy (HAART). Most conditions associated with IRIS are infectious. Malignancies, such as Kaposi's sarcoma, have also been reported. We report a case of sinusitis with presumptive inflammatory pseudotumor as a manifestation of IRIS that occurred 20 weeks after the initiation of HAART.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • AIDS-Related Opportunistic Infections / pathology*
  • Adult
  • Antiretroviral Therapy, Highly Active / adverse effects*
  • CD4 Lymphocyte Count
  • Granuloma, Plasma Cell / complications
  • Granuloma, Plasma Cell / physiopathology*
  • HIV Infections / drug therapy*
  • Humans
  • Male
  • Sinusitis / chemically induced*
  • Sinusitis / diagnosis
  • Sinusitis / pathology