[Fibrocystic mastopathy and cancer of the breast. About 111 cases]

Tunis Med. 2006 Oct;84(10):626-31.
[Article in French]

Abstract

Objective: Our aim was to identify the predictive factors of degeneration of the fibrocystic mastopathy.

Methods: This work is a retrospective survey of 111 observations of isolated fibrocystic mastopathies or associated to a breast cancer among 542 women admitted for tumor of the breast during one period of 13 active years from 1991 to 2003. The diagnosis has been gotten by anatomo-pathologic exam in 95.5% (106 cas) on the operative piece and 4.5% (5 cas) on a material of biopsy.

Results: The fibrocystic mastopathy represented 30% of the set of the benign tumors of the breast. They were associated to a breast cancer in 45 cases (40.5%). The isolated benign fibrocystic mastopathy was observed in 66 cases with a middle age of 37 years, whereas the shapes associated to a breast carcinoma were noted in 45 cases. The middle age was 53 years. The non proliferative fibrocystic mastopathy is the most frequent histological type and represent 54.6% of the cases. The proliferative form with atypies was observed at 21 women (46.8%). The carcinoma the more frequently associated to the fibrocystic mastopathy was the infiltrating canalled carcinoma in 91% of cases, with a predominance of the II rank (SBR).

Conclusion: The discovery of a mastopathy must search a luteal failure and risk factors of breast cancer notably a proliferative shape of mastopathy with atypies.

Publication types

  • Comparative Study
  • English Abstract

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Biopsy
  • Breast / pathology
  • Breast Neoplasms* / complications
  • Breast Neoplasms* / diagnosis
  • Breast Neoplasms* / pathology
  • Carcinoma, Ductal, Breast* / complications
  • Carcinoma, Ductal, Breast* / diagnosis
  • Chi-Square Distribution
  • Data Interpretation, Statistical
  • Female
  • Fibrocystic Breast Disease* / classification
  • Fibrocystic Breast Disease* / complications
  • Fibrocystic Breast Disease* / diagnosis
  • Fibrocystic Breast Disease* / pathology
  • Humans
  • Menopause
  • Middle Aged
  • Neoplasm Staging
  • Parity
  • Predictive Value of Tests
  • Pregnancy
  • Retrospective Studies
  • Risk
  • Risk Factors
  • Ultrasonography, Mammary