Objective: Primary solitary fibrous tumors (SFTs) of the female genital tract are exceedingly rare. We report a spindle cell tumor of the vagina with features consistent with a SFT in a 52-year-old woman.
Materials and methods: The original tumor was studied with the appropriate panel of immunohistochemical stains. The first recurrence of the tumor was 10 months after its original incomplete excision, and a second recurrence occurred 29 months later. Both recurrences were analyzed using the same immunohistochemical panel.
Results: After considering several related differential diagnoses, the diagnosis of SFT was made based on the morphological and immunophenotypic features.
Conclusion: To the best of our knowledge, this is the third case of vaginal SFT in the English literature, with 2 recurrences after incomplete excision.