[A case of progressive gastric carcinoma accompanied by disseminated carcinomatosis of bone marrow due to bone metastasis with DIC recovery by joint administration of 5-FU and paclitaxel]

Gan To Kagaku Ryoho. 2006 Dec;33(13):2079-81.
[Article in Japanese]

Abstract

A 54-year-old male visited our hospital with the chief complaint of anorexia. Based on various tests, a diagnosis of scirrhous gastric carcinoma accompanied by bone metastasis and liver metastasis was made. As DIC developed following hospital admission, 5-FU and PTX therapy (5-FU at 600 mg/m(2), 24-hour continuous infusion, day 1-5 and PTX at 80 mg/m(2), iv, day 8, 15, 22) were administered. Although primary foci, bone metastasis, and liver metastasis were observed by image diagnostic procedures, recovery from DIC was achieved. 5-FU+PTX therapy is considered to be effective for DIC due to bone metastasis of gastric carcinoma.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adenocarcinoma, Scirrhous / drug therapy*
  • Adenocarcinoma, Scirrhous / secondary
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Bone Marrow Neoplasms / drug therapy*
  • Bone Marrow Neoplasms / secondary
  • Bone Neoplasms / drug therapy*
  • Bone Neoplasms / secondary
  • Disseminated Intravascular Coagulation / etiology*
  • Drug Administration Schedule
  • Fluorouracil / administration & dosage
  • Humans
  • Liver Neoplasms / drug therapy*
  • Liver Neoplasms / secondary
  • Male
  • Middle Aged
  • Paclitaxel / administration & dosage
  • Stomach Neoplasms / drug therapy*
  • Stomach Neoplasms / pathology*

Substances

  • Paclitaxel
  • Fluorouracil