Evaluation of x-ray diffraction enhanced imaging in the diagnosis of breast cancer

Phys Med Biol. 2007 Jan 21;52(2):419-27. doi: 10.1088/0031-9155/52/2/008. Epub 2006 Dec 29.

Abstract

The significance of the x-ray diffraction enhanced imaging (DEI) technique in the diagnosis of breast cancer and its feasibility in clinical medical imaging are evaluated. Different massive specimens including normal breast tissues, benign breast tumour tissues and malignant breast tumour tissues are imaged with the DEI method. The images are recorded respectively by CCD or x-ray film at different positions of the rocking curve and processed with a pixel-by-pixel algorithm. The characteristics of the DEI images about the normal and diseased tissues are compared. The rocking curves of a double-crystal diffractometer with various tissues are also studied. The differences in DEI images and their rocking curves are evaluated for early diagnosis of breast cancers.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Absorption
  • Algorithms
  • Breast / pathology
  • Breast Neoplasms / diagnosis*
  • Breast Neoplasms / diagnostic imaging*
  • Female
  • Humans
  • Image Enhancement / methods
  • Image Processing, Computer-Assisted / methods
  • Mammography / methods*
  • Radiographic Image Enhancement
  • Radiographic Image Interpretation, Computer-Assisted
  • Scattering, Radiation
  • X-Ray Diffraction
  • X-Rays