MascotDatfile: an open-source library to fully parse and analyse MASCOT MS/MS search results

Proteomics. 2007 Feb;7(3):364-6. doi: 10.1002/pmic.200600682.

Abstract

MS-based protein identification is an important part of both gel-based and gel-free proteome studies. The MASCOT search engine (http://www.matrixscience.com) provides one of the most popular automated algorithms for this task. Here we present an open-source software library written in Java that parses raw MASCOT results into an easily accessible and fully functional object model (http://genesis.ugent.be/MascotDatfile). Several scripts based on this library are provided as examples, allowing direct automation of important routine tasks involved in processing peptide identifications.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • Computational Biology*
  • Databases, Protein*
  • Peptide Library*
  • Software*
  • Tandem Mass Spectrometry*

Substances

  • Peptide Library