Cross-reactions between respiratory and food allergens

Allergy Proc. 1991 Sep-Oct;12(5):313-7. doi: 10.2500/108854191778879151.

Abstract

Cross-reactions between inhaled and food allergens are usually attributed to pollen hypersensitivity associated with fruit and vegetable allergy. However, other allergens are involved in these types of cross-reactions. In a few cases, there is a complete similarity between the inhaled and food allergens (garlic, crustacea proteins). More frequently, partial similarity has been demonstrated: whole inhaled allergens are included in ingested substances. Moreover, immunological techniques can demonstrate common antigenic epitopes in organic substances without any apparent relationship. This has been demonstrated by RAST-inhibition and/or immunoblot techniques, using sera from patients cross-sensitized to (1) pollens and fruits or vegetables or (2) avian sera and eggs. Respiratory sensitization always seems to precede food allergy symptoms.

MeSH terms

  • Allergens / immunology*
  • Cross Reactions
  • Enzyme-Linked Immunosorbent Assay
  • Epitopes
  • Food Hypersensitivity / immunology*
  • Humans
  • Occupational Diseases / immunology
  • Pollen / immunology
  • Radioallergosorbent Test
  • Respiratory Hypersensitivity / immunology*

Substances

  • Allergens
  • Epitopes