Abstract
The aim of this study was to characterize the molecular features of serogroup C Neisseria meningitidis strains circulating in Beijing, China. Twenty out of 23 strains belonged to ST 4821. The causative serosubtype for meningococcal meningitis was P1.12-1,16-8. All of the strains expressed class 3 PorB protein. Among the five pulsed-field gel electrophoresis patterns observed, pattern III predominated.
MeSH terms
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Bacterial Typing Techniques
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Carrier State / epidemiology
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Carrier State / microbiology
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China / epidemiology
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Electrophoresis, Gel, Pulsed-Field
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Humans
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Meningitis, Meningococcal / epidemiology*
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Meningitis, Meningococcal / microbiology*
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Neisseria meningitidis, Serogroup C / classification*
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Neisseria meningitidis, Serogroup C / genetics*
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Phosphotransferases (Carboxyl Group Acceptor)
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Sequence Analysis, DNA
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Serotyping
Substances
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Phosphotransferases (Carboxyl Group Acceptor)
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glutamate 5-kinase