CSF pressure assessed by lumbar puncture agrees with intracranial pressure

N Lenfeldt; L-O D Koskinen; A T Bergenheim; J Malm; A Eklund

doi:10.1212/01.wnl.0000250270.54587.71

CSF pressure assessed by lumbar puncture agrees with intracranial pressure

Neurology. 2007 Jan 9;68(2):155-8. doi: 10.1212/01.wnl.0000250270.54587.71.

Authors

N Lenfeldt¹, L-O D Koskinen, A T Bergenheim, J Malm, A Eklund

Affiliation

¹ Department of Clinical Neuroscience, Umeå University, S-901 85 Umeå, Sweden. [email protected]

PMID: 17210899
DOI: 10.1212/01.wnl.0000250270.54587.71

Abstract

The accuracy of estimating intracranial pressure in brain tissue (ICP(BT)) via lumbar space was investigated using preset pressure levels in the interval 0 to 600 mm H(2)O in patients with communicating hydrocephalus. Lumbar space ICP correlated excellently to ICP(BT), demonstrated by a measured mean difference of 10 mm H(2)O (0.75 mm Hg) and a regression coefficient of 0.98. The concurrence supports the lumbar puncture as an accurate technique to determine ICP in patients with communicating CSF systems.

Publication types

Controlled Clinical Trial
Research Support, Non-U.S. Gov't

MeSH terms

Aged
Cerebrospinal Fluid*
Female
Humans
Hydrocephalus, Normal Pressure / diagnosis*
Hydrocephalus, Normal Pressure / physiopathology*
Intracranial Pressure*
Male
Manometry / methods*
Reproducibility of Results
Sensitivity and Specificity
Spinal Puncture / methods*