Purtscher-like retinopathy as an initial presentation of a thrombotic microangiopathy associated with antineoplastic therapy

Am J Hematol. 2007 Jun;82(6):486-8. doi: 10.1002/ajh.20845.

Abstract

We describe the case of a 31-year-old female with Hodgkin's lymphoma who developed renal and retinal thrombotic microangiopathy (TM) months after autologous bone marrow transplantation. Presenting symptoms were ocular and examination findings were consistent with a Purtscher-like retinopathy. This case demonstrates that patients being treated with antineoplastic therapy who develop TM should have an ocular examination for Purtscher retinopathy. The visual prognosis of Purtscher retinopathy is guarded.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antineoplastic Agents / adverse effects*
  • Bone Marrow Transplantation / adverse effects*
  • Female
  • Follow-Up Studies
  • Glucocorticoids / therapeutic use
  • Hodgkin Disease / complications
  • Hodgkin Disease / diagnosis
  • Hodgkin Disease / therapy*
  • Humans
  • Kidney Diseases / diagnosis
  • Kidney Diseases / drug therapy
  • Kidney Diseases / etiology*
  • Methylprednisolone / therapeutic use*
  • Recurrence
  • Retinal Diseases / diagnosis
  • Retinal Diseases / drug therapy
  • Retinal Diseases / etiology*
  • Thrombosis / diagnosis
  • Thrombosis / etiology*
  • Thrombosis / therapy
  • Transplantation, Autologous
  • Treatment Outcome

Substances

  • Antineoplastic Agents
  • Glucocorticoids
  • Methylprednisolone