Pregnancy-associated recurrent liver necrosis in patient with antiphospholipid syndrome

V M Ulander; V Stefanovic; I Rinta-Kiikka; R Kaaja

doi:10.1177/0961203306072385

Pregnancy-associated recurrent liver necrosis in patient with antiphospholipid syndrome

Lupus. 2006;15(12):889-91. doi: 10.1177/0961203306072385.

Authors

V M Ulander¹, V Stefanovic, I Rinta-Kiikka, R Kaaja

Affiliation

¹ Department of Obstetrics and Gynecology, Helsinki University Central Hospital, Helsinki, Finland.

PMID: 17211997
DOI: 10.1177/0961203306072385

Abstract

The presence of antiphospholipid antibodies is associated with thromboembolic events, thrombocytopenia and numerous pregnancy complications such as recurrent miscarriage, preeclampsia and HELLP syndrome. This condition is known as the antiphospholipid syndrome (APS). We describe a rare case of recurrent liver necrosis postpartum in two consecutive pregnancies of woman with systemic lupus erythematosus (SLE) and positive antiphospholipid antibodies (aPL) who underwent complete recovery.

Publication types

Case Reports

MeSH terms

Adult
Antibodies, Antiphospholipid / blood
Anticoagulants / therapeutic use
Antiphospholipid Syndrome / complications*
Antiphospholipid Syndrome / drug therapy
Antiphospholipid Syndrome / immunology
Female
Heparin, Low-Molecular-Weight / therapeutic use
Humans
Liver Diseases / etiology*
Liver Diseases / pathology*
Magnetic Resonance Imaging
Necrosis
Pregnancy
Pregnancy Complications / etiology*
Pregnancy Complications / pathology*
Recurrence
Warfarin / therapeutic use

Substances

Antibodies, Antiphospholipid
Anticoagulants
Heparin, Low-Molecular-Weight
Warfarin